| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1007153 |
| landingPage: |
http://www.iedb.org/assay/1581121 |
| type: |
Literature
|
| publicationVenue: |
Microbiology
|
| dates: |
1996
|
| study type: | b cell assays |
| subject species: | Neisseria meningitidis serogroup B H44/76 |
| fullName: |
A A Delvig
E Wedege
T E Michaelsen
E A Hø
iby
P Brandtzaeg
E Rosenqvist
|
| method: |
ELISA
|
| name: |
Immune responses to linear epitopes on the PorB protein of Neisseria meningitidis in patients with systemic meningococcal disease.
|
| description: |
Several peptides containing the sequence FHQNGQVTE and including either residues VTT at the C-terminus or residues SV at the N-terminus were recognized by systemic meningococcal disease patients. The pin-bound peptides covering this region were recognized, but a free peptide covering the region FHQNGQVTEVTTATGI was not. The authors conclude that reactivity by pepscan is due to the high concentration of pin-bound peptide, facilitating bivalent reactions and cross-reactivity. A longer peptide (D63b2) encompassing the region could be recognized in solution.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |