Antigenic determinants of the cholera/coli family of enterotoxins. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Antigenic determinants of the cholera/coli family of enterotoxins.

Dataset

identifier:	1587671
description:	epitope description:VEVPGSQHIDSQ antigen name:Cholera enterotoxin subunit B host organism:Oryctolagus cuniculus antibody name:Rabbit sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	2446368

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1012838
landingPage:	http://www.iedb.org/assay/1587671

Publication

type:	Literature
publicationVenue:	Rev Infect Dis
dates:	1987

Dimension

study type:	b cell assays
subject species:	Vibrio cholerae 569B

Person

fullName:	R A Finkelstein M F Burks A Zupan W S Dallas C O Jacob D S Ludwig

Data Type

method:	ELISA

Study

name:	Antigenic determinants of the cholera/coli family of enterotoxins.
description:	Rabbits immunized with the larger peptide 45-64 conjugated to TT reacted well with the shorter epitope, aa50-61. The authors deduced aa50-61 as the epitope. This sera was also capable of reacting with the B subunit of the heat-labile enterotoxin (H-LT) of both human and porcine strains of E. coli, as well as human-porcine chimeric proteins with mutations at residues 4, 13, 46, and 102.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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