Alternative forms of a strain-specific neutralizing antigenic site on the Sindbis virus E2 glycoprotein.

Title:

Alternative forms of a strain-specific neutralizing antigenic site on the Sindbis virus E2 glycoprotein.

identifier:	1587674
description:	epitope description:K27 antigen name:Structural polyprotein host organism:Mus musculus BALB/c antibody name:18, 23
aggregation:	instance of dataset
availability:	available
primaryPublications:	2445100

study type:	b cell assays
subject species:	Sindbis virus

fullName:	N L Davis D F Pence W J Meyer A L Schmaljohn R E Johnston

method:	ELISA

name:	Alternative forms of a strain-specific neutralizing antigenic site on the Sindbis virus E2 glycoprotein.
description:	The sequence of E2 protein is found in Strauss et al. (1984) [PMID: 6322438]. The epitope-specific mAbs bound the virus when residue 216 was Lys, but not Glu or Val. Escape mutants confirmed K216 as the epitope.

name:	iedb
homePage:	http://www.iedb.org

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