Molecular recognition of botulinum neurotoxin B heavy chain by human antibodies from cervical dystonia patients that develop immunoresistance to toxin treatment.

Title:

Molecular recognition of botulinum neurotoxin B heavy chain by human antibodies from cervical dystonia patients that develop immunoresistance to toxin treatment.

Dataset

identifier:	1587875
description:	epitope description:NKVVEAGLFAGWVKQIVND antigen name:Botulinum neurotoxin type B host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	18676021

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1013271
landingPage:	http://www.iedb.org/assay/1587875

Publication

type:	Literature
publicationVenue:	Mol Immunol
dates:	2008

Dimension

study type:	b cell assays
subject species:	Clostridium botulinum B

Person

fullName:	M Zouhair Atassi Behzod Z Dolimbek Joseph Jankovic Lance E Steward K Roger Aoki

Data Type

method:	radio immuno assay (RIA)

Study

name:	Molecular recognition of botulinum neurotoxin B heavy chain by human antibodies from cervical dystonia patients that develop immunoresistance to toxin treatment.
description:	Sera were tested individually or as a pool of the 30 individual sera. This peptide showed very low or no detectable Ab binding in 6 or less of the sera.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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