Protective immunogenicity and T lymphocyte specificity of a trivalent hybrid peptide containing NH2-terminal sequences of types 5, 6, and 24 M proteins synthesized in tandem.

Title:

Protective immunogenicity and T lymphocyte specificity of a trivalent hybrid peptide containing NH2-terminal sequences of types 5, 6, and 24 M proteins synthesized in tandem.

Dataset

identifier:	1583888
description:	epitope description:TVTRGTISDPRVFPRGTVENPVATRSQTDTSEKDC host organism:Oryctolagus cuniculus New Zealand White
aggregation:	instance of dataset
availability:	available
primaryPublications:	2442284

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1011207
landingPage:	http://www.iedb.org/assay/1583888

Publication

type:	Literature
publicationVenue:	J Exp Med
dates:	1987

Dimension

study type:	b cell assays
subject species:

Person

fullName:	E H Beachey J M Seyer J B Dale

Data Type

method:	biological activity

Study

name:	Protective immunogenicity and T lymphocyte specificity of a trivalent hybrid peptide containing NH2-terminal sequences of types 5, 6, and 24 M proteins synthesized in tandem.
description:	The epitope is a hybrid molecule composed of 3 separate peptides from the M protein of serotypes M5, M6, and M24. The rabbit antisera was able to opsonize and kill Streptococcus pyogenes serotype M24.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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