Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1010424 |
| landingPage: |
http://www.iedb.org/assay/1585738 |
| type: |
Literature
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| publicationVenue: |
J Immunol
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| dates: |
1985
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| study type: | b cell assays |
| subject species: | Tobacco mosaic virus |
| fullName: |
F L Norton
P R Morrow
C Y Leung
E Benjamini
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| method: |
radio immuno assay (RIA)
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| name: |
The idiotypic characterization of the immune response to a defined epitope of a protein antigen and the specific in vivo suppression of the immune response to this epitope by anti-idiotypic antibodies.
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| description: |
The anti-TMVP antibodies also recognized the epitope analog with methione substitution at residue tyrosine 5. Binding of the epitope to the anti-TMVP antibodes was inhibited when mice were pre-treated in vivo by administration of anti-idiotypic antibodies to an epitope-specific mAb. This inhibition was not observed in C.AL-20 mice.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
