Monoclonal antibodies to scorpion toxins. Characterization and molecular mechanisms of neutralization.

Title:

Monoclonal antibodies to scorpion toxins. Characterization and molecular mechanisms of neutralization.

identifier:	1585747
description:	epitope description:K58 antigen name:Alpha-mammal toxin AaH2 host organism:Mus musculus BALB/c antibody name:4C1
aggregation:	instance of dataset
availability:	available
primaryPublications:	2454259

study type:	b cell assays
subject species:	Androctonus australis hector

fullName:	E Bahraoui J Pichon J M Muller H Darbon M Elayeb C Granier J Marvaldi H Rochat

method:	biological activity

name:	Monoclonal antibodies to scorpion toxins. Characterization and molecular mechanisms of neutralization.
description:	The epitope residue is found in Bahraoui et al. (1986) [PMID: 3958496]. The epitope-specific mAb was able to neutralize AaH toxin II both by binding to toxin before it was injected into mice and by inhibition of binding of toxin to synaptosomes in vitro.

name:	iedb
homePage:	http://www.iedb.org

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