Mapping of immunogenic regions of human T cell leukemia virus type I (HTLV-I) gp46 and gp21 envelope glycoproteins with env-encoded synthetic peptides and a monoclonal antibody to gp46.

Title:

Mapping of immunogenic regions of human T cell leukemia virus type I (HTLV-I) gp46 and gp21 envelope glycoproteins with env-encoded synthetic peptides and a monoclonal antibody to gp46.

Dataset

identifier:	1587153
description:	epitope description:LLPHSNLDHILEPSIPWKSK antigen name:Envelope glycoprotein gp62 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	2563272

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1013597
landingPage:	http://www.iedb.org/assay/1587153

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	1989

Dimension

study type:	b cell assays
subject species:	Human T-lymphotropic virus 1

Person

fullName:	T J Palker M E Tanner R M Scearce R D Streilein M E Clark B F Haynes

Data Type

method:	cross blocking

Study

name:	Mapping of immunogenic regions of human T cell leukemia virus type I (HTLV-I) gp46 and gp21 envelope glycoproteins with env-encoded synthetic peptides and a monoclonal antibody to gp46.
description:	The epotipe contained an additional N-terminal cysteine and C-terminal tyrosine residue. The epitope-specific mAb 1C11 inhibited the binding of the HTLV-1+ patient sera to the antigen in ELISA and Immonoblot.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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