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Title: Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.
identifier: 1594094
description:
epitope description:K585, F586, K587, V588, V589, K590, I592, Q605, P644, K668, N670
antigen name:Genome polyprotein
host organism:Mus musculus BALB/c
antibody name:1A1D-2
aggregation:
instance of dataset
availability:
available
primaryPublications: 18264114
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1013023
landingPage: http://www.iedb.org/assay/1594094
type:
Literature
publicationVenue:
Nat Struct Mol Biol
dates:
2008
study type: b cell assays
subject species: Dengue virus 2 Thailand/16681/84
fullName:
Shee-Mei Lok
Victor Kostyuchenko
Grant E Nybakken
Heather A Holdaway
Anthony J Battisti
Soila Sukupolvi-Petty
Dagmar Sedlak
Daved H Fremont
Paul R Chipman
John T Roehrig
Michael S Diamond
Richard J Kuhn
Michael G Rossmann
method:
biological activity
name:
Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.
description:
Epitope-specific mAb 1A1D-2 neutralized DENV serotype 2, and serotypes 1 and 3 at higher concentrations of antibody.

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