Nuclear magnetic resonance structure and IgE epitopes of Blo t 5, a major dust mite allergen. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Nuclear magnetic resonance structure and IgE epitopes of Blo t 5, a major dust mite allergen.

Dataset

identifier:	1594108
description:	epitope description:LLIEQANHAIEKGEHQ antigen name:Blo t 5 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	18684949

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1013253
landingPage:	http://www.iedb.org/assay/1594108

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	2008

Dimension

study type:	b cell assays
subject species:	Blomia tropicalis

Person

fullName:	Siew Leong Chan Tan Ching Ong Yun Feng Gao Yuen Sung Tiong De Yun Wang Fook Tim Chew Yu Keung Mok

Data Type

method:	ELISA

Study

name:	Nuclear magnetic resonance structure and IgE epitopes of Blo t 5, a major dust mite allergen.
description:	The epitope was tested as the solid-phase antigen in a biotin-SGSG-peptide-amide format. For 1/8 patients, the Blo t 5 carrying an Alanine mutation at residue E37 had a significant (>20%) reduction in IgE binding.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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