Peptide vaccines incorporating a 'promiscuous' T-cell epitope bypass certain haplotype restricted immune responses and provide broad spectrum immunogenicity.

Title:

Peptide vaccines incorporating a 'promiscuous' T-cell epitope bypass certain haplotype restricted immune responses and provide broad spectrum immunogenicity.

Dataset

identifier:	1587986
description:	epitope description:VDDALIDSTKIYSYFPSV antigen name:Tetanus toxin host organism:Oryctolagus cuniculus New Zealand White
aggregation:	instance of dataset
availability:	available
primaryPublications:	7508238

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1013037
landingPage:	http://www.iedb.org/assay/1587986

Publication

type:	Literature
publicationVenue:	J Mol Recognit
dates:	1993

Dimension

study type:	b cell assays
subject species:	Clostridium tetani

Person

fullName:	P T Kaumaya S Kobs-Conrad Y H Seo H Lee A M VanBuskirk N Feng J F Sheridan V Stevens

Data Type

method:	ELISA

Study

name:	Peptide vaccines incorporating a 'promiscuous' T-cell epitope bypass certain haplotype restricted immune responses and provide broad spectrum immunogenicity.
description:	The response to tetanus toxin was positive when the epitope was linked to GPSLELEGLLKKLLDTLENMLK, but not when linked to GPSLELEGLLKKSADTLWNMQK.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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