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Title: Human rotavirus VP4 contains strain-specific, serotype-specific and cross-reactive neutralization sites.
identifier: 1588307
description:
epitope description:S397
antigen name:Outer capsid protein VP4
host organism:Mus musculus BALB/c
antibody name:ST-3:3
aggregation:
instance of dataset
availability:
available
primaryPublications: 8645097
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1013378
landingPage: http://www.iedb.org/assay/1588307
type:
Literature
publicationVenue:
Arch Virol
dates:
1996
study type: b cell assays
subject species: Human rotavirus G4 strain St. Thomas 3
fullName:
C D Kirkwood
R F Bishop
B S Coulson
method:
biological activity
name:
Human rotavirus VP4 contains strain-specific, serotype-specific and cross-reactive neutralization sites.
description:
The epitopic residue recognized by the mAb was determined by sequence analysis of neutralization-resistant variants of the virus isolated after growth in the presence of the mAb. Variants with mutation S397R in VP4 (VP5* subunit) were not neutralized by the mAb.

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