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Title: Host genetic and adjuvant factors influence epitope specificity to a major recombinant grass allergen.
identifier: 1589072
description:
epitope description:AFKVAATAANAAPANDKFTV
antigen name:Poa p 5
host organism:Mus musculus C57BL/6
aggregation:
instance of dataset
availability:
available
primaryPublications: 8859227
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1005260
landingPage: http://www.iedb.org/assay/1589072
type:
Literature
publicationVenue:
Int Arch Allergy Immunol
dates:
1996
study type: b cell assays
subject species: Poa pratensis
fullName:
M Yang
Y Y Wang
L Zhang
P Chong
S S Mohapatra
method:
ELISA
name:
Host genetic and adjuvant factors influence epitope specificity to a major recombinant grass allergen.
description:
Mice immunized with major allergen rKBG were screened for reactivity against 24 overlapping peptides spanning the length of the protein. The use of different adjuvants influenced the reactivity to rKBG peptides. CFA induced reactivity to domains 1 (residues 151-200) and 2 (residues 251-290), whereas dextran sulfate induced reactivity to only domain 1.

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