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identifier: 1589195
description:
epitope description:PNSWYGAGAIKMSGPNNHV
antigen name:UniProt:I6TX52
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 7520424
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1008774
landingPage: http://www.iedb.org/assay/1589195
type:
Literature
publicationVenue:
Infect Immun
dates:
1994
study type: b cell assays
subject species: Streptococcus mutans
fullName:
K Matsushita
T Nisizawa
S Nagaoka
M Kawagoe
method:
ELISA
name:
Identification of antigenic epitopes in a surface protein antigen of Streptococcus mutans in humans.
description:
A cysteine residue was placed at the C-terminus of all 20-mer synthetic peptides for peptide purification by HPLC.
Serum Abs (IgG, IgM and IgA) of 5 adult (A to E) and one 4-month-old infant were assayed. Patient A (A11, Aw33, B44, DRw6(w13), DRw8, DRw52, DQwl), patient B (All, Aw33, B44, Cw7, DR2(w15), Rw6(w13), DRw52, DQwl(DQw5)), patient C (A24, All, Bw52, B7, Cw7, DR1, DR2(w15), DQwl(DQw5, w6)), patient D (A2, A31, Bw48, Cw4, DR2(wl5), DR9, DRw53, DQwl(DQw6)) and patient E (A24, A31, Bw6l, BwS9, Cwl, Cw3, DR1, DR9, DRw53, DQwl(DQw5), DQw9) tested positive with the 7 PAc-derived peptides of serotype c S. mutans. .

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