| Title: | Identification of antigenic epitopes in a surface protein antigen of Streptococcus mutans in humans. |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1008774 |
| landingPage: |
http://www.iedb.org/assay/1589195 |
| type: |
Literature
|
| publicationVenue: |
Infect Immun
|
| dates: |
1994
|
| study type: | b cell assays |
| subject species: | Streptococcus mutans |
| fullName: |
K Matsushita
T Nisizawa
S Nagaoka
M Kawagoe
|
| method: |
ELISA
|
| name: |
Identification of antigenic epitopes in a surface protein antigen of Streptococcus mutans in humans.
|
| description: |
A cysteine residue was placed at the C-terminus of all 20-mer synthetic peptides for peptide purification by HPLC.
Serum Abs (IgG, IgM and IgA) of 5 adult (A to E) and one 4-month-old infant were assayed. Patient A (A11, Aw33, B44, DRw6(w13), DRw8, DRw52, DQwl), patient B (All, Aw33, B44, Cw7, DR2(w15), Rw6(w13), DRw52, DQwl(DQw5)), patient C (A24, All, Bw52, B7, Cw7, DR1, DR2(w15), DQwl(DQw5, w6)), patient D (A2, A31, Bw48, Cw4, DR2(wl5), DR9, DRw53, DQwl(DQw6)) and patient E (A24, A31, Bw6l, BwS9, Cwl, Cw3, DR1, DR9, DRw53, DQwl(DQw5), DQw9) tested positive with the 7 PAc-derived peptides of serotype c S. mutans. .
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |