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Title: Cross-reactive and serotype-specific neutralization epitopes on VP7 of human rotavirus: nucleotide sequence analysis of antigenic mutants selected with monoclonal antibodies.
identifier: 1590166
description:
epitope description:D213
antigen name:Outer capsid glycoprotein VP7
host organism:Mus musculus
antibody name:KU-4
aggregation:
instance of dataset
availability:
available
primaryPublications: 2452893
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1011516
landingPage: http://www.iedb.org/assay/1590166
type:
Literature
publicationVenue:
J Virol
dates:
1988
study type: b cell assays
subject species: Human rotavirus strain KU
fullName:
K Taniguchi
Y Hoshino
K Nishikawa
K Y Green
W L Maloy
Y Morita
S Urasawa
A Z Kapikian
R M Chanock
M Gorziglia
method:
biological activity
name:
Cross-reactive and serotype-specific neutralization epitopes on VP7 of human rotavirus: nucleotide sequence analysis of antigenic mutants selected with monoclonal antibodies.
description:
The epitope-specific mAb was able to neutralize human rotavirus KU. Mutant escape virus selected with the serotype 1-specific mAb was found to have a mutation at the epitopic residue in VP7.

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