Identification of common epitopes on gliadin, enterocytes, and calreticulin recognised by antigliadin antibodies of patients with coeliac disease.

Title:

Identification of common epitopes on gliadin, enterocytes, and calreticulin recognised by antigliadin antibodies of patients with coeliac disease.

Dataset

identifier:	1593108
description:	epitope description:YPQPQPFPSQQP antigen name:Other Triticum aestivum (Canadian hard winter wheat) protein host organism:Homo sapiens antibody name:anti-gliadin antibodies (AGA)
aggregation:	instance of dataset
availability:	available
primaryPublications:	9895374

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1005168
landingPage:	http://www.iedb.org/assay/1593108

Publication

type:	Literature
publicationVenue:	Gut
dates:	1999

Dimension

study type:	b cell assays
subject species:	Triticum aestivum

Person

fullName:	S Krupicková L Tucková Z Flegelová M Michalak J R Walters A Whelan J Harries J Vencovský H Tlaskalová -Hogenová

Data Type

method:	antigen inhibition

Study

name:	Identification of common epitopes on gliadin, enterocytes, and calreticulin recognised by antigliadin antibodies of patients with coeliac disease.
description:	The epitope inhibited the binding to gliadin of anti-gliadin antibodies (AGA) isolated from 4 of 6 celiac disease patients. The epitope also inhibited the binding of 5 of 9 AGA to rat enterocytes. The epitope partially inhibited binding of two patients' AGA tested to calreticulin.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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