Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1010670 |
| landingPage: |
http://www.iedb.org/assay/1594965 |
| type: |
Literature
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| publicationVenue: |
Virology
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| dates: |
1995
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| study type: | b cell assays |
| subject species: | Foot-and-mouth disease virus C-S8c1 |
| fullName: |
M G Mateu
D Andreu
E Domingo
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| method: |
antigen inhibition
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| name: |
Antibodies raised in a natural host and monoclonal antibodies recognize similar antigenic features of foot-and-mouth disease virus.
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| description: |
The sera from infected and vaccinated swine recognized the epitope and a number of tested analogs of the epitope. Substitution at position 11 (H146) greatly diminished binding. Alanine substitution at positions 5-7 (RGD) strongly affected reactivity, although substitution of Arg had a less pronounced effect than substitution of Gly or Asp. The peptide was synthesized to contain a C-terminal cysteine residue for conjugation to KLH.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
