Naturally occurring mutations within 39 amino acids in the envelope glycoprotein of maedi-visna virus alter the neutralization phenotype.

Title:

Naturally occurring mutations within 39 amino acids in the envelope glycoprotein of maedi-visna virus alter the neutralization phenotype.

identifier:	1596469
description:	epitope description:GRDFWGKVKAKY antigen name:envelope polyprotein host organism:Ovis aries
aggregation:	instance of dataset
availability:	available
primaryPublications:	10482555

study type:	b cell assays
subject species:	Visna/maedi virus EV1 KV1772

fullName:	R Skraban S Matthí asdó ttir S Torsteinsdó G Agnarsdó B Gudmundsson G Georgsson R H Meloen O S André sson K A Staskus H Thormar V André sdó

method:	ELISA

name:	Naturally occurring mutations within 39 amino acids in the envelope glycoprotein of maedi-visna virus alter the neutralization phenotype.
description:	The strain used is KV1772kv72/67, which is a molecular clone derived from strain KV1772. Similar results were obtained when the immunogen was a recombinant virus where a 39-aa region of the envelope protein of strain LV1-1KS1 substituted the homolog sequence of KV1772kv72/67 (at residues 559-597, containing the epitope).

name:	iedb
homePage:	http://www.iedb.org

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.