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identifier: 1599747
description:
epitope description:A: H44, Q46, D47, I48, S304, M305, P306, T331; B: D365, G366, W367, K384, T387, Q388, I391, D392, T395, V398, N399, I402;
antigen name:Hemagglutinin
host organism:Homo sapiens
antibody name:CR6261
aggregation:
instance of dataset
availability:
available
primaryPublications: 19251591
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1013930
landingPage: http://www.iedb.org/assay/1599747
type:
Literature
publicationVenue:
Science
dates:
2009
study type: b cell assays
subject species: Influenza A virus (A/Viet Nam/1203/2004(H5N1))
fullName:
Damian C Ekiert
Gira Bhabha
Marc-André
Elsliger
Robert H E Friesen
Mandy Jongeneelen
Mark Throsby
Jaap Goudsmit
Ian A Wilson
method:
biological activity
name:
Antibody recognition of a highly conserved influenza virus epitope.
description:
The epitope-specific CR6261 Fab inhibits the pH-induced conversion of hemagglutinin to the protease susceptible conformation associated with membrane fusion.

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