IgE from latex-allergic patients binds to cloned and expressed B cell epitopes of prohevein. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

IgE from latex-allergic patients binds to cloned and expressed B cell epitopes of prohevein.

Dataset

identifier:	1602874
description:	epitope description:PYSWRSKYGW antigen name:Hev b 6 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	9548517

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1013974
landingPage:	http://www.iedb.org/assay/1602874

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	1997

Dimension

study type:	b cell assays
subject species:	Hevea brasiliensis

Person

fullName:	B Banerjee X Wang K J Kelly J N Fink G L Sussman V P Kurup

Data Type

method:	western blot

Study

name:	IgE from latex-allergic patients binds to cloned and expressed B cell epitopes of prohevein.
description:	Pooled serum IgE from health care workers with latex allergy or spina bifida patients with latex allergy reacted with the epitope in a pepscan analysis of overlapping peptides from prohevein. The common sequence of decapeptides from this region binding to IgE from HCW was PYSWRSK (residues 87-93). The common sequence binding to IgE from SB patients was PYSWR, which was part of the epitope PYSWRSKYDW (residues 87-96).

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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