Radiobinding assay for detecting autoantibodies to single epitopes. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Radiobinding assay for detecting autoantibodies to single epitopes.

Dataset

identifier:	1606362
description:	epitope description:KERLAALGPEGAH antigen name:Receptor-type tyrosine-protein phosphatase-like N host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	18501377

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1012466
landingPage:	http://www.iedb.org/assay/1606362

Publication

type:	Literature
publicationVenue:	J Immunol Methods
dates:	2008

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Vito Lampasona Cristina Belloni Sandra Piquer Sara Bonicchio Roberto Furlan Ezio Bonifacio

Data Type

method:	immunoprecipitation

Study

name:	Radiobinding assay for detecting autoantibodies to single epitopes.
description:	Sera from diabetic patients recognized the epitope by radiobinding assay (RBA) and by ELISA, with the ELISA being less sensitive than the RBA. TrxA protein and the epitope were able to compete for the binding of the sera to the epitope. Of 4 donors who were IA-2 antibody positive, 1 reacted with the epitope by immunoprecipitation.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.