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Title: Enhanced immunogenicity of Plasmodium falciparum peptide vaccines using a topical adjuvant containing a potent synthetic Toll-like receptor 7 agonist, imiquimod.
identifier: 1605395
description:
epitope description:DPNANPNVDPNANPNVNANPNANPNANPEYLNKIQNSLSTEWSPCSVT
host organism:Mus musculus C57BL/6
aggregation:
instance of dataset
availability:
available
primaryPublications: 19047411
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1013678
landingPage: http://www.iedb.org/assay/1605395
type:
Literature
publicationVenue:
Infect Immun
dates:
2009
study type: b cell assays
subject species:
fullName:
Caroline Othoro
Dean Johnston
Rebecca Lee
Jonathan Soverow
Jean-Claude Bystryn
Elizabeth Nardin
method:
in vivo assay
name:
Enhanced immunogenicity of Plasmodium falciparum peptide vaccines using a topical adjuvant containing a potent synthetic Toll-like receptor 7 agonist, imiquimod.
description:
The epitope sequence was described in Calvo-Calle et al, Infect Immun: 74(12) 2006 [PMID 17030584].
Epitope immunized mice were protected against P. falciparum challenge as measured by parasite and RNA burden in liver samples.

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