Fine specificity of monoclonal antibodies against celiac disease-inducing peptides in the gluteome.

Title:

Fine specificity of monoclonal antibodies against celiac disease-inducing peptides in the gluteome.

identifier:	1605435
description:	epitope description:PPFSQQ antigen name:Uncharacterized protein (UniProt:Q8W3V4) host organism:Mus musculus BALB/c antibody name:anti-LMW-1 glt
aggregation:	instance of dataset
availability:	available
primaryPublications:	18842794

study type:	b cell assays
subject species:	Triticum aestivum

fullName:	Cristina Mitea Yvonne Kooy-Winkelaar Peter van Veelen Arnoud de Ru Jan W Drijfhout Frits Koning Liesbeth Dekking

method:	immunoprecipitation

name:	Fine specificity of monoclonal antibodies against celiac disease-inducing peptides in the gluteome.
description:	The epitope-specific mAb immunoprecipitated the peptide from a pepsin/trypsin digest of wheat gluten. The mAb also immunoprecipitated the peptide SQQQPPFWQQQPPFSQQQPIL. The results show that the mAb reacts with gluten peptides that are naturally formed during digestion in the gastrointestinal tract resulting from the activity of pepsin and trypsin.

name:	iedb
homePage:	http://www.iedb.org

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