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Title: Sequential B-cell epitopes of Bacillus anthracis lethal factor bind lethal toxin-neutralizing antibodies.
identifier: 1605764
description:
epitope description:VTNYLVDGNG
antigen name:Lethal factor
host organism:Mus musculus C57BL/6 X BALB/c
antibody name:9A11
aggregation:
instance of dataset
availability:
available
primaryPublications: 18981257
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1014009
landingPage: http://www.iedb.org/assay/1605764
type:
Literature
publicationVenue:
Infect Immun
dates:
2009
study type: b cell assays
subject species: Bacillus anthracis
fullName:
Melissa L Nguyen
Sherry R Crowe
Sridevi Kurella
Simon Teryzan
Brian Cao
Jimmy D Ballard
Judith A James
A Darise Farris
method:
antigen inhibition
name:
Sequential B-cell epitopes of Bacillus anthracis lethal factor bind lethal toxin-neutralizing antibodies.
description:
This peptide is part of the domain IV of Lethal factor, involved in the zinc metalloproteinase function.
The epitope inhibited the neutralization by the epitope-specific mAb of the lethal toxin killing of macrophages.

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