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Title: Transcutaneous beta-amyloid immunization reduces cerebral beta-amyloid deposits without T cell infiltration and microhemorrhage.
identifier: 1617953
description:
epitope description:DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
antigen name:Amyloid beta A4 protein
host organism:Mus musculus APPsw
aggregation:
instance of dataset
availability:
available
primaryPublications: 17264212
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1003692
landingPage: http://www.iedb.org/assay/1617953
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
2007
study type: b cell assays
subject species: Homo sapiens
fullName:
William V Nikolic
Yun Bai
Demian Obregon
Huayan Hou
Takashi Mori
Jin Zeng
Jared Ehrhart
R Douglas Shytle
Brian Giunta
Dave Morgan
Terrence Town
Jun Tan
method:
ELISA
name:
Transcutaneous beta-amyloid immunization reduces cerebral beta-amyloid deposits without T cell infiltration and microhemorrhage.
description:
Increased plasma levels of antibody to A beta 1-40 were detected, but levels of brain soluble A beta 1-40 antibodies were decreased compared with non-vaccinated mice.

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