Identification and characterization of nematode specific protective epitopes of Brugia malayi TRX towards development of synthetic vaccine construct for lymphatic filariasis.

Title:

Identification and characterization of nematode specific protective epitopes of Brugia malayi TRX towards development of synthetic vaccine construct for lymphatic filariasis.

Dataset

identifier:	1794173
description:	epitope description:ADLLANINLKKADGTVKKGSDALANK antigen name:Bm9804 host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	20653106

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1020928
landingPage:	http://www.iedb.org/assay/1794173

Publication

type:	Literature
publicationVenue:	Vaccine
dates:	2010

Dimension

study type:	b cell assays
subject species:	Brugia malayi

Person

fullName:	Jayaprakasam Madhumathi Prabhu Rajaiah Prince Gandhirajan Anugraha Pote Kiran Donthamsetty Nageswara Rao Maryada Venkata Rami Reddy Perumal Kaliraj

Data Type

method:	antigen inhibition

Study

name:	Identification and characterization of nematode specific protective epitopes of Brugia malayi TRX towards development of synthetic vaccine construct for lymphatic filariasis.
description:	The epitope inhibited the binding of epitope-specific sera. The peptide-specific response was also significantly greater for TRX P1 than TRX P2, though both were co-administered, as shown in direct ELISA. Responses peaked day 60 post-immunization.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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