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Title: Development of peptide mimics of a protective epitope of Vibrio cholerae Ogawa O-antigen and investigation of the structural basis of peptide mimicry.
identifier: 1795394
description:
epitope description:SHRLPLK
host organism:Mus musculus BALB/c
antibody name:S-20-4 and A-20-6
aggregation:
instance of dataset
availability:
available
primaryPublications: 17881351
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1007663
landingPage: http://www.iedb.org/assay/1795394
type:
Literature
publicationVenue:
J Biol Chem
dates:
2007
study type: b cell assays
subject species:
fullName:
Madushini N Dharmasena
David A Jewell
Ronald K Taylor
method:
phage display
name:
Development of peptide mimics of a protective epitope of Vibrio cholerae Ogawa O-antigen and investigation of the structural basis of peptide mimicry.
description:
This epitope is a structural peptide mimic of the Ogawa O-antigen from Vibrio cholera O1.
Phage display libraries were biopanned against mAbs S-20-4 and S-20-6, which are specific for the protective epitope of Ogawa LPS, using low pH elution or non-elution. This unique sequence bound both monoclonal antibodies.

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