Broad cross-protection against H5N1 avian influenza virus infection by means of monoclonal antibodies that map to conserved viral epitopes.

Title:

Broad cross-protection against H5N1 avian influenza virus infection by means of monoclonal antibodies that map to conserved viral epitopes.

identifier:	1627663
description:	epitope description:K168, N198 antigen name:Hemagglutinin host organism:Mus musculus BALB/c antibody name:20A11, 16F13, 13D4, 16G3, 20H2, 14E4
aggregation:	instance of dataset
availability:	available
primaryPublications:	19032063

study type:	b cell assays
subject species:	Influenza A virus (A/Vietnam/1194/2004(H5N1))

fullName:	Yixin Chen Kun Qin Wai Lan Wu Guoqiang Li Jun Zhang Hailian Du Mun Hon Ng J Wai-Kuo Shih J S Malik Peiris Yi Guan Honglin Chen Ningshao Xia

method:	biological activity

name:	Broad cross-protection against H5N1 avian influenza virus infection by means of monoclonal antibodies that map to conserved viral epitopes.
description:	The epitope-specific mAbs were broadly cross-reactive to 41 H5N1 isolates belonging to 8 major genetic clades/subclades (0–9), while no cross-reactivity with 4 non–H5 viruses (2 H3N2 and 2 H1N1) was observed.

name:	iedb
homePage:	http://www.iedb.org

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