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Title: Autoreactive epitopes defined by diabetes-associated human monoclonal antibodies are localized in the middle and C-terminal domains of the smaller form of glutamate decarboxylase.
identifier: 1637604
description:
epitope description:VSYQPLGDKVNFFRMVISNPAATHQDIDFLIEEIERLGQDL
antigen name:Glutamate decarboxylase 2
host organism:Homo sapiens
antibody name:MICA 2
aggregation:
instance of dataset
availability:
available
primaryPublications: 7681990
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1006884
landingPage: http://www.iedb.org/assay/1637604
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
1993
study type: b cell assays
subject species: Homo sapiens
fullName:
W Richter
Y Shi
S Baekkeskov
method:
western blot
name:
Autoreactive epitopes defined by diabetes-associated human monoclonal antibodies are localized in the middle and C-terminal domains of the smaller form of glutamate decarboxylase.
description:
The epitope sequence is from the reference cited: Karlsen et al. (1991) Proc. Natl. Acad. Sci. U.S.A. 88: 8337-8341 [PMID: 1924293]. The epitope was deduced.
The epitope-specific human mAb MICA 2 reacted with GAD65 by Western blotting.

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