Identification of biologically active peptides that inhibit binding of human CXCL8 to its receptors from a random phage-epitope library.

Title:

Identification of biologically active peptides that inhibit binding of human CXCL8 to its receptors from a random phage-epitope library.

identifier:	1632450
description:	epitope description:SDWWDF host organism:Mus musculus antibody name:anti-CXCR1 mAb 5A12
aggregation:	instance of dataset
availability:	available
primaryPublications:	19118103

study type:	b cell assays
subject species:

fullName:	Mehdi Houimel Luca Mazzucchelli

method:	ELISA

name:	Identification of biologically active peptides that inhibit binding of human CXCL8 to its receptors from a random phage-epitope library.
description:	Epitopes were identified in a phage display experiment with anti-CXCR1 mAb 5A12. Synthetic peptides corresponding to the phage-peptides were synthesized and tested for binding to the same mAb by ELISA, inhibition of binding of the mAb to the phage-peptide, and inhibition of binding of the mAb to CXCR1.

name:	iedb
homePage:	http://www.iedb.org

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