Characterisation of an autoreactive conformational epitope on GAD65 recognised by the human monoclonal antibody b78 using a combination of phage display, in vitro mutagenesis and molecular modelling.

Title:

Characterisation of an autoreactive conformational epitope on GAD65 recognised by the human monoclonal antibody b78 using a combination of phage display, in vitro mutagenesis and molecular modelling.

Dataset

identifier:	1632506
description:	epitope description:PNAPDAS host organism:Mus musculus antibody name:GAD6
aggregation:	instance of dataset
availability:	available
primaryPublications:	16564157

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1014290
landingPage:	http://www.iedb.org/assay/1632506

Publication

type:	Literature
publicationVenue:	J Autoimmun
dates:	2006

Dimension

study type:	b cell assays
subject species:

Person

fullName:	Karen H O'Connor J Paul Banga Connie Darmanin Ossama El-Kabbani Ian R Mackay Merrill J Rowley

Data Type

method:	phage display

Study

name:	Characterisation of an autoreactive conformational epitope on GAD65 recognised by the human monoclonal antibody b78 using a combination of phage display, in vitro mutagenesis and molecular modelling.
description:	The epitope was part of a cysteine-constrained random phage library.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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