| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1006196 |
| landingPage: |
http://www.iedb.org/assay/1634867 |
| type: |
Literature
|
| publicationVenue: |
Proc Natl Acad Sci U S A
|
| dates: |
2001
|
| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
R B DeMattos
K R Bales
D J Cummins
J C Dodart
S M Paul
D M Holtzman
|
| method: |
immuno staining
|
| name: |
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease.
|
| description: |
The epitope-specific mAb, when given to APP mice, was able to change the equilibrium of APP in the plasma and increase it 1000-fold, compared to non-treated APP mice.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |