Immunological Data Discovery Index
Advanced Search
identifier: 1634867
description:
epitope description:HHQKLVFFAEDVGSNK
antigen name:Amyloid beta A4 protein
host organism:Mus musculus
aggregation:
instance of dataset
availability:
available
primaryPublications: 11438712
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1006196
landingPage: http://www.iedb.org/assay/1634867
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
2001
study type: b cell assays
subject species: Homo sapiens
fullName:
R B DeMattos
K R Bales
D J Cummins
J C Dodart
S M Paul
D M Holtzman
method:
immuno staining
name:
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease.
description:
The epitope-specific mAb, when given to APP mice, was able to change the equilibrium of APP in the plasma and increase it 1000-fold, compared to non-treated APP mice.

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.