Direct detection of disease associated prions in brain and lymphoid tissue using antibodies recognizing the extreme N terminus of PrPC.

Title:

Direct detection of disease associated prions in brain and lymphoid tissue using antibodies recognizing the extreme N terminus of PrPC.

identifier:	1635044
description:	epitope description:KKRPKPGGGWNT antigen name:Major prion protein host organism:Homo sapiens antibody name:YMH2
aggregation:	instance of dataset
availability:	available
primaryPublications:	19164886

study type:	b cell assays
subject species:	Bos taurus

fullName:	Geoff Barnard Lee Hopkins Sowmiya Moorthie David Seilly Paul Tonks Reza Dabaghian Jonathan Clewley John Coward Ian McConnell

method:	antigen inhibition

name:	Direct detection of disease associated prions in brain and lymphoid tissue using antibodies recognizing the extreme N terminus of PrPC.
description:	Epitope specificity, determined by the percentage of maximum binding between the MAb and PrP in the presence of competing peptide, was assayed by competitive inhibition using a time-resolved fluorometric (TRF) immunoassay (DELFIA).

name:	iedb
homePage:	http://www.iedb.org

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