Immunotherapy reduces vascular amyloid-beta in PDAPP mice. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Immunotherapy reduces vascular amyloid-beta in PDAPP mice.

Dataset

identifier:	1638064
description:	epitope description:KLVFFAE antigen name:Amyloid beta A4 protein host organism:Mus musculus
aggregation:	instance of dataset
availability:	available
primaryPublications:	18596154

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1013109
landingPage:	http://www.iedb.org/assay/1638064

Publication

type:	Literature
publicationVenue:	J Neurosci
dates:	2008

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Sally Schroeter Karen Khan Robin Barbour Minhtam Doan Ming Chen Terry Guido Davinder Gill Guriqbal Basi Dale Schenk Peter Seubert Dora Games

Data Type

method:	in vivo assay

Study

name:	Immunotherapy reduces vascular amyloid-beta in PDAPP mice.
description:	Treatment of APP mice with the epitope-specific mAb was not able to prevent or clear vascular amyloid beta in a dose-dependent manner, compared to treatment with a control antibody.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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