Immunological Data Discovery Index
Advanced Search
  1. << Go Back
Title: Mature high-affinity immune responses to (pro)insulin anticipate the autoimmune cascade that leads to type 1 diabetes.
identifier: 1639074
description:
epitope description:F25, V26, N27, E37, R46, T51, P52, K53, T54, T85, S86, I87, S89, L90, Y91, Q92, E94
antigen name:Insulin (UniProt:A6XGL2)
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 15314696
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1014336
landingPage: http://www.iedb.org/assay/1639074
type:
Literature
publicationVenue:
J Clin Invest
dates:
2004
study type: b cell assays
subject species: Homo sapiens
fullName:
Peter Achenbach
Kerstin Koczwara
Annette Knopff
Heike Naserke
Anette-G Ziegler
Ezio Bonifacio
method:
antigen inhibition
name:
Mature high-affinity immune responses to (pro)insulin anticipate the autoimmune cascade that leads to type 1 diabetes.
description:
Binding of sera to insulin is not blocked by cold competitor with polymorphisms at F25, V26, N27, E37, R46, T51, P52, K53, T54, T86, S86, I87, S89, L90, Y91, and Q92.

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.

ImmuneData is supported by the NIAID, Grant HHSN272201700019C. Privacy

ImmuneData is developed by TechWave International, Inc. and UT Health Science Center at Houston