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Title: Reduced oligomeric and vascular amyloid-beta following immunization of TgCRND8 mice with an Alzheimer's DNA vaccine.
identifier: 1641168
description:
epitope description:DAEFRHDSGYEVHHQKLVFFAEDVGSNK
antigen name:Amyloid beta A4 protein
host organism:Mus musculus APPsw
aggregation:
instance of dataset
availability:
available
primaryPublications: 19150380
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1014204
landingPage: http://www.iedb.org/assay/1641168
type:
Literature
publicationVenue:
Vaccine
dates:
2009
study type: b cell assays
subject species: Homo sapiens
fullName:
Kevin A DaSilva
Mary E Brown
JoAnne McLaurin
method:
ELISA
name:
Reduced oligomeric and vascular amyloid-beta following immunization of TgCRND8 mice with an Alzheimer's DNA vaccine.
description:
Mice injected with either wild-type A beta 1-42, A beta 1-42 bound to caspase or a mutant A beta 1-42 with a change at E22G bound to caspase, all produced antibody to the epitope, with the wild type A beta 1-42 producing the most antibody.

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