Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1001803 |
| landingPage: |
http://www.iedb.org/assay/1641309 |
| type: |
Literature
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| publicationVenue: |
Proc Natl Acad Sci U S A
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| dates: |
2001
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| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
A Monsonego
R Maron
V Zota
D J Selkoe
H L Weiner
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| method: |
immuno staining
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| name: |
Immune hyporesponsiveness to amyloid beta-peptide in amyloid precursor protein transgenic mice: implications for the pathogenesis and treatment of Alzheimer's disease.
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| description: |
Sera from immunzied APP transgenic mice (APP-Tg+), which express beta-amyloid precursor protein, stained only a few neuritic plaques compared with strong staining observed with sera from control B6SJL mice and non-transgenic (wild-type) littermates of APP-Tg+ mice. The fewer number of stained plaques observed with serum was expected due to the low anti-epitope antibody titers in the immunized APP-Tg+ mice.
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| name: |
iedb
|
| homePage: |
http://www.iedb.org |
