Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology.

Title:

Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology.

identifier:	1642078
description:	epitope description:EFRHD antigen name:Amyloid beta A4 protein host organism:Mus musculus antibody name:6C6, 10D5
aggregation:	instance of dataset
availability:	available
primaryPublications:	12566568

study type:	b cell assays
subject species:	Homo sapiens

fullName:	Fré dé rique Bard Robin Barbour Catherine Cannon Robert Carretto Michael Fox Dora Games Teresa Guido Kathleen Hoenow Kang Hu Kelly Johnson-Wood Karen Khan Dora Kholodenko Celeste Lee Mike Lee Ruth Motter Minh Nguyen Amanda Reed Dale Schenk Pearl Tang Nicki Vasquez Peter Seubert Ted Yednock

method:	ELISA

name:	Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology.
description:	The epitope-specific mAbs bound to aggregated A beta 1-42, but not as effectively to the soluble peptide. The ED50 for binding to aggregated A beta 1-42 for 6C6 was 40 pM, and for 10D5 was 53 pM.

name:	iedb
homePage:	http://www.iedb.org

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