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Title: Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology.
identifier: 1642109
description:
epitope description:EFRHD
antigen name:Amyloid beta A4 protein
host organism:Mus musculus
aggregation:
instance of dataset
availability:
available
primaryPublications: 12566568
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1010842
landingPage: http://www.iedb.org/assay/1642109
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
2003
study type: b cell assays
subject species: Homo sapiens
fullName:
Fré
dé
rique Bard
Robin Barbour
Catherine Cannon
Robert Carretto
Michael Fox
Dora Games
Teresa Guido
Kathleen Hoenow
Kang Hu
Kelly Johnson-Wood
Karen Khan
Dora Kholodenko
Celeste Lee
Mike Lee
Ruth Motter
Minh Nguyen
Amanda Reed
Dale Schenk
Pearl Tang
Nicki Vasquez
Peter Seubert
Ted Yednock
method:
in vivo assay
name:
Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology.
description:
The epitope-specific mAbs were able to reduce Alzheimer's-like neuropathology and clear amyloid plaques in mice given the mAbs, compared to controls.

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