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Title: Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy.
identifier: 1642521
description:
epitope description:DAEFRHDSGYEDAEFRHDSGYEDAEFRHDSGYE
host organism:Mus musculus C57BL/6
aggregation:
instance of dataset
availability:
available
primaryPublications: 18461171
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1012439
landingPage: http://www.iedb.org/assay/1642521
type:
Literature
publicationVenue:
PLoS One
dates:
2008
study type: b cell assays
subject species:
fullName:
Nina Movsesyan
Anahit Ghochikyan
Mikayel Mkrtichyan
Irina Petrushina
Hayk Davtyan
Purevdorj B Olkhanud
Elizabeth Head
Arya Biragyn
David H Cribbs
Michael G Agadjanyan
method:
ELISA
name:
Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy.
description:
Epitope DNA vaccination induced strong amyloid beta-specific Ab, which recognized human Amyloid beta deposits when used in direct immunohistochemical stainings in an Alzheimer’s Disease case. Immunized 3XTg-AD mice also showed a strong amyloid beta-specific Ab titer.

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