Disaggregation of Alzheimer beta-amyloid by site-directed mAb. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Disaggregation of Alzheimer beta-amyloid by site-directed mAb.

Dataset

identifier:	1642527
description:	epitope description:DAEFRHDSGYEVHHQK antigen name:Amyloid beta A4 protein host organism:Mus musculus antibody name:6C6
aggregation:	instance of dataset
availability:	available
primaryPublications:	9108113

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1014425
landingPage:	http://www.iedb.org/assay/1642527

Publication

type:	Literature
publicationVenue:	Proc Natl Acad Sci U S A
dates:	1997

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	B Solomon R Koppel D Frankel E Hanan-Aharon

Data Type

method:	biological activity

Study

name:	Disaggregation of Alzheimer beta-amyloid by site-directed mAb.
description:	The epitope-specific mAb was able to resolubilize fibrillar A beta 1-42. It was also able to reduce the beta amyloid neurotoxicity toward in vitro cultured neuronal cells.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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