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Title: Epitope mapping and neuroprotective properties of a human single chain FV antibody that binds an internal epitope of amyloid-beta 1-42.
identifier: 1642502
description:
epitope description:VHHQKLVFFAEDVGSNK
antigen name:Amyloid beta A4 protein
host organism:Homo sapiens
antibody name:b4.4
aggregation:
instance of dataset
availability:
available
primaryPublications: 17889938
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1014421
landingPage: http://www.iedb.org/assay/1642502
type:
Literature
publicationVenue:
Mol Immunol
dates:
2008
study type: b cell assays
subject species: Homo sapiens
fullName:
R S Soló
rzano-Vargas
V Vasilevko
G Acero
K E Ugen
R Martinez
T Govezensky
R Vazquez-Ramirez
C Kubli-Garfias
D H Cribbs
K Manoutcharian
G Gevorkian
method:
biological activity
name:
Epitope mapping and neuroprotective properties of a human single chain FV antibody that binds an internal epitope of amyloid-beta 1-42.
description:
The epitope-specific scFv was able to reduce A beta 1-42 induced neurotoxicity in vitro.

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