Development of a monoclonal antibody specific for the COOH-terminal of beta-amyloid 1-42 and its immunohistochemical reactivity in Alzheimer's disease and related disorders.

Title:

Development of a monoclonal antibody specific for the COOH-terminal of beta-amyloid 1-42 and its immunohistochemical reactivity in Alzheimer's disease and related disorders.

Dataset

identifier:	1642677
description:	epitope description:VGGVVIA antigen name:Amyloid beta A4 protein host organism:Mus musculus antibody name:108.1
aggregation:	instance of dataset
availability:	available
primaryPublications:	8178931

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1008563
landingPage:	http://www.iedb.org/assay/1642677

Publication

type:	Literature
publicationVenue:	Am J Pathol
dates:	1994

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	G M Murphy Jr L S Forno L Higgins J M Scardina L F Eng B Cordell

Data Type

method:	antigen inhibition

Study

name:	Development of a monoclonal antibody specific for the COOH-terminal of beta-amyloid 1-42 and its immunohistochemical reactivity in Alzheimer's disease and related disorders.
description:	Preincubation of epitope-specific mAb with beta-amyloid (1-42) fragment blocked the mAb staining of plaques in Alzheimer's disease brain sections.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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