Immunological Data Discovery Index
Advanced Search
identifier: 1642590
description:
epitope description:RARGRGRGRGEKRP
antigen name:Epstein-Barr nuclear antigen 1
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 2164400
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1004452
landingPage: http://www.iedb.org/assay/1642590
type:
Literature
publicationVenue:
Arthritis Rheum
dates:
1990
study type: b cell assays
subject species: Human gammaherpesvirus 4
fullName:
J Petersen
G Rhodes
J Roudier
J H Vaughan
method:
ELISA
name:
Altered immune response to glycine-rich sequences of Epstein-Barr nuclear antigen-1 in patients with rheumatoid arthritis and systemic lupus erythematosus.
description:
Patients with rheumatoid arthritis had a significantly higher antibody response to the epitope than normal subjects with viral capsid antibody. (Normal subjects without VCA were negative.) Patients with SLE or Hashimoto's thyroiditis also had an elevated antibody response. Patients with progressive systemic sclerosis or Graves' disease were positive, but not not significantly different than normal subjects with viral capsid antibody.

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.