Immunogenicity and therapeutic efficacy of phage-displayed beta-amyloid epitopes. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Immunogenicity and therapeutic efficacy of phage-displayed beta-amyloid epitopes.

Dataset

identifier:	1643083
description:	epitope description:AEFRH antigen name:Amyloid beta A4 protein host organism:Mus musculus APP
aggregation:	instance of dataset
availability:	available
primaryPublications:	17850871

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1011664
landingPage:	http://www.iedb.org/assay/1643083

Publication

type:	Literature
publicationVenue:	Mol Immunol
dates:	2008

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Marianna Esposito Ilaria Luccarini Valeria Cicatiello Diana De Falco Anna Fiorentini Pasquale Barba Fiorella Casamenti Antonella Prisco

Data Type

method:	in vivo assay

Study

name:	Immunogenicity and therapeutic efficacy of phage-displayed beta-amyloid epitopes.
description:	Mice transgenic for human APP were treated with several doses of the epitope, and had a reduction in amyloid plaques in both the cortex and hippocampus. Mice given one prime-boost cycle did not see a reduction compared to untreated mice.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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