Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice.

Title:

Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice.

identifier:	1643982
description:	epitope description:DAEFRHDSGYEVHHQ antigen name:Amyloid beta A4 protein host organism:Mus musculus APP
aggregation:	instance of dataset
availability:	available
primaryPublications:	17517595

study type:	b cell assays
subject species:	Homo sapiens

fullName:	Andreas Muhs David T Hickman Maria Pihlgren Nathalie Chuard Valé rie Giriens Carine Meerschman Ingrid van der Auwera Fred van Leuven Masae Sugawara Marie-Catherine Weingertner Burkhard Bechinger Ruth Greferath Nadine Kolonko Luitgard Nagel-Steger Detlev Riesner Roscoe O Brady Andrea Pfeifer Claude Nicolau

method:	in vivo assay

name:	Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice.
description:	Immunization of APPxPS1 double transgenic mice with the epitope reduced the symptoms of Alzheimer's Disease including cognition tests and amount of Abeta in the brain.

name:	iedb
homePage:	http://www.iedb.org

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