Conformational and linear B-cell epitopes of Asp f 2, a major allergen of Aspergillus fumigatus, bind differently to immunoglobulin E antibody in the sera of allergic bronchopulmonary aspergillosis patients.

Title:

Dataset

identifier:	1644361
description:	epitope description:YTTRR antigen name:Asp f 2 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	10225885

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1014766
landingPage:	http://www.iedb.org/assay/1644361

Publication

type:	Literature
publicationVenue:	Infect Immun
dates:	1999

Dimension

study type:	b cell assays
subject species:	Aspergillus fumigatus

Person

fullName:	B Banerjee P A Greenberger J N Fink V P Kurup

Data Type

method:	western blot

Study

name:	Conformational and linear B-cell epitopes of Asp f 2, a major allergen of Aspergillus fumigatus, bind differently to immunoglobulin E antibody in the sera of allergic bronchopulmonary aspergillosis patients.
description:	The epitope was determined to be the minimal epitope recognized by sera from patients with ABPA through analysis of overlapping 5-amino acid peptides spanning the reactive peptide 110-119 (DRSYTTRRWL). Adding 5 Ala residues to the N- or C-terminus reduced binding.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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