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Title: Direct in vivo intracellular selection of conformation-sensitive antibody domains targeting Alzheimer's amyloid-beta oligomers.
identifier: 1644856
description:
epitope description:DAEFGHDSGF
antigen name:Amyloid beta A4 protein
host organism:Mus musculus BALB/c
antibody name:Im47
aggregation:
instance of dataset
availability:
available
primaryPublications: 19361429
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1014195
landingPage: http://www.iedb.org/assay/1644856
type:
Literature
publicationVenue:
J Mol Biol
dates:
2009
study type: b cell assays
subject species: Mus musculus
fullName:
Giovanni Meli
Michela Visintin
Isabella Cannistraci
Antonino Cattaneo
method:
biological activity
name:
Direct in vivo intracellular selection of conformation-sensitive antibody domains targeting Alzheimer's amyloid-beta oligomers.
description:
The epitope specific monoclonal single chain Fv antibody fragments neutralized the apoptotic effects of Abeta-derived diffusible ligands (ADDLs) in SHSY5Y neuroblastoma cells.

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