Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1014564 |
| landingPage: |
http://www.iedb.org/assay/1649757 |
| type: |
Literature
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| publicationVenue: |
Eur J Immunol
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| dates: |
2001
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| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
H G Kraetsch
C Unger
P Wernhoff
C Schneider
J R Kalden
R Holmdahl
H Burkhardt
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| method: |
ELISA
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| name: |
Cartilage-specific autoimmunity in rheumatoid arthritis: characterization of a triple helical B cell epitope in the integrin-binding-domain of collagen type II.
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| description: |
Serum from a patient with severe rheumatoid arthritis, on the basis of high anti-CII autoantibody levels, recognized the epitope by ELISA. The exact epitope residues were identified by truncation mapping with CII fragment constructs, and epitope binding was also with a peptide competition ELISA. Patient follow-up over a 4-year period reflects the influences of disease activity and treatments on anti-epitope autoantibody levels.
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| name: |
iedb
|
| homePage: |
http://www.iedb.org |
