Analysis of collagenase-cleavage of type II collagen using a neoepitope ELISA. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Analysis of collagenase-cleavage of type II collagen using a neoepitope ELISA.

Dataset

identifier:	1649822
description:	epitope description:GPPGPQG antigen name:Collagen alpha-1(II) chain host organism:Mus musculus BALB/c antibody name:9A4
aggregation:	instance of dataset
availability:	available
primaryPublications:	11150534

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1008362
landingPage:	http://www.iedb.org/assay/1649822

Publication

type:	Literature
publicationVenue:	J Immunol Methods
dates:	2001

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	J T Downs C L Lane N B Nestor T J McLellan M A Kelly G A Karam P S Mezes J P Pelletier I G Otterness

Data Type

method:	ELISA

Study

name:	Analysis of collagenase-cleavage of type II collagen using a neoepitope ELISA.
description:	Information on the epitope can be found in Otterness et al. Matrix Biol. 1999 Aug 18(4):331-41. [PMID: 10517180] The epitope-specific mAb 9A4 was used to detect cleavage fragments of the source antigen (human type II collagen); it detected collagen in urine samples from osteoarthritic individuals (9/10) and healthy controls (2/10).

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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